PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24733347-0	2014	An agomir of miR-144-3p accelerates plaque formation through impairing reverse cholesterol transport and promoting pro-inflammatory cytokine production.	Cholesterol	79-90	microRNA 144	Homo sapiens	13-20	
24733347-4	2014	Moreover, miR-144-3p mimics (agomir) enhanced the expression of inflammatory factors, including IL-1beta, IL-6 and TNF-alpha, in vivo and in vitro, inhibited cholesterol efflux in THP-1 macrophage-derived foam cells, decreased HDL-C circulation and impaired RCT in vivo, resulting in accelerated pathological progression of atherosclerosis in apoE-/- mice.	Cholesterol	158-169	microRNA 144	Homo sapiens	10-17	
24733347-6	2014	CONCLUSIONS: Our findings clearly indicate that miR-144-3p is essential for the regulation of cholesterol homeostasis and inflammatory reactions, supporting its utility as a potential therapeutic target of atherosclerosis and a promising diagnostic biomarker of AMI.	Cholesterol	94-105	microRNA 144	Homo sapiens	48-55	
31724712-11	2020	In the hepatocytes of yellow catfish, miR-144 inversely regulated the expression of hmgcr, cyp7a1, and abca1 (30.3-78.5%, P < 0.05); loss of miR-144 function alleviated PA- or OA-induced cholesterol accumulation (19.5-61.1%, P < 0.05).	Cholesterol	190-201	microRNA 144	Homo sapiens	38-45	
31724712-13	2020	CONCLUSIONS: miR-144 mediated HFD-induced changes in the liver and hepatocytes of yellow catfish, suggesting a possible mechanism for HFD-induced dysfunction in cholesterol metabolism.	Cholesterol	161-172	microRNA 144	Homo sapiens	13-20	
29772548-4	2018	Accumulating studies have revealed that miRNAs such as miR-33, miR-27, miR-144, miR-758 and miR-20 are involved in the post-transcriptional control of ABCA1, ABCG1 and SCARB1 genes regulatory network of the reverse cholesterol transport (RCT).	Cholesterol	215-226	microRNA 144	Homo sapiens	71-78	
31724712-0	2020	miR-144 Mediates High Fat-Induced Changes of Cholesterol Metabolism via Direct Regulation of C/EBPalpha in the Liver and Isolated Hepatocytes of Yellow Catfish.	Cholesterol	45-56	microRNA 144	Homo sapiens	0-7	
31724712-10	2020	miR-144 directly targeted hydroxymethylglutaryl-CoA reductase (hmgcr), cholesterol 7alpha-monooxygenase A1 (cyp7a1), and adenosine triphosphate binding cassette transporter A1 (abca1) in HEK293T cells.	Cholesterol	71-82	microRNA 144	Homo sapiens	0-7	
31852219-10	2020	CONCLUSIONS: Our data demonstrate silencing miR-144 has sex-specific effects and that treatment with antisense oligonucleotides to target miR-144 might result in enhancements in reverse cholesterol transport and oxysterol metabolism in patients with cardiovascular disease.	Cholesterol	186-197	microRNA 144	Homo sapiens	44-51	
31852219-10	2020	CONCLUSIONS: Our data demonstrate silencing miR-144 has sex-specific effects and that treatment with antisense oligonucleotides to target miR-144 might result in enhancements in reverse cholesterol transport and oxysterol metabolism in patients with cardiovascular disease.	Cholesterol	186-197	microRNA 144	Homo sapiens	138-145	
26945479-2	2016	miR-33 and miR-144 regulate adenosine triphosphate binding cassette transporter (ABCA1) and other target genes involved in cholesterol efflux, fatty acid oxidation and inflammation.	Cholesterol	123-134	microRNA 144	Homo sapiens	11-18