PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29562399-8	2018	In multivariate analysis, age, eGFR, serum cholesterol level and 24 h urinary protein quantification were independent factors of serum IGFBP-3 in patients with CKD (R2=0.243, P<0.001).	Cholesterol	43-54	insulin like growth factor binding protein 3	Homo sapiens	135-142	
24743393-5	2014	RESULTS: In cross-sectional analyses, we detected that IGF1 and IGFBP3 levels were positively related to total and LDL cholesterol and inversely related to HDL cholesterol in both sexes.	Cholesterol	119-130	insulin like growth factor binding protein 3	Homo sapiens	64-70	
24825082-8	2014	In addition, serum IGFBP-3 levels showed significant positive correlation with HbA1c, total cholesterol, and LDL-cholesterol in the uncontrolled diabetic patients.	Cholesterol	92-103	insulin like growth factor binding protein 3	Homo sapiens	19-26	
24825082-8	2014	In addition, serum IGFBP-3 levels showed significant positive correlation with HbA1c, total cholesterol, and LDL-cholesterol in the uncontrolled diabetic patients.	Cholesterol	113-124	insulin like growth factor binding protein 3	Homo sapiens	19-26	
24743393-5	2014	RESULTS: In cross-sectional analyses, we detected that IGF1 and IGFBP3 levels were positively related to total and LDL cholesterol and inversely related to HDL cholesterol in both sexes.	Cholesterol	160-171	insulin like growth factor binding protein 3	Homo sapiens	64-70	
16075928-10	2005	In conclusion, IGF-I and IGFBP-3 were negatively correlated with common cardiovascular risk factors, studied as total/HDL-cholesterol ratio, and/or early atherosclerosis, studied as IMT at common carotid arteries.	Cholesterol	122-133	insulin like growth factor binding protein 3	Homo sapiens	25-32	
16614079-0	2006	Insulin-like growth factor binding protein 3 has opposing actions on malignant and nonmalignant breast epithelial cells that are each reversible and dependent upon cholesterol-stabilized integrin receptor complexes.	Cholesterol	164-175	insulin like growth factor binding protein 3	Homo sapiens	0-44	
16614079-5	2006	IGFBP-3 also promoted survival of Hs578T cells in the presence of an antibody to the beta1-integrin subunit or when cholesterol-stabilized complexes were disrupted.	Cholesterol	116-127	insulin like growth factor binding protein 3	Homo sapiens	0-7	
16614079-8	2006	In contrast, IGFBP-3 promoted growth and survival for nonmalignant MCF-10A cells, but these effects were again reversed on fibronectin and blocked by the beta1 antibody or a MAPK inhibitor or by disruption of cholesterol-stabilized complexes.	Cholesterol	209-220	insulin like growth factor binding protein 3	Homo sapiens	13-20	
16614079-10	2006	In summary, with three breast epithelial cell lines, IGFBP-3 had positive or negative effects on growth and survival dependent upon the status of cholesterol-stabilized integrin receptor complexes.	Cholesterol	146-157	insulin like growth factor binding protein 3	Homo sapiens	53-60	
15466497-5	2004	Longitudinally, a 1,000-ng/ml increase in IGFBP-3 was associated with 3.7-mg/dl and 2.6-mg/dl higher total cholesterol levels and 2.6-mg/dl and 1.7-mg/dl higher low density lipoprotein cholesterol levels in Black men and White men (p < 0.05), respectively.	Cholesterol	107-118	insulin like growth factor binding protein 3	Homo sapiens	42-49	
15625284-10	2005	Blood pressure, total cholesterol, triglyceride, and visceral adipose tissue were positively associated with IGFBP-3.	Cholesterol	22-33	insulin like growth factor binding protein 3	Homo sapiens	109-116	
14576164-10	2004	Co-treatment with anti-transferrin receptor antibody and cholesterol depletion agents completely abolished endogenous and exogenous IGFBP-3 uptake.	Cholesterol	57-68	insulin like growth factor binding protein 3	Homo sapiens	132-139	
12944034-9	2003	Multiple logistic regression analysis revealed that the IGFBP-3 level was associated with a ninefold (95% confidence interval 2.6-31) higher risk of carotid plaque formation compared with LDL cholesterol or IGF-1 levels.	Cholesterol	192-203	insulin like growth factor binding protein 3	Homo sapiens	56-63	
35187107-9	2021	Among them, insulin-like growth factor binding protein-3 is positively associated with RF, lower BMI, and HDL-cholesterol, renin with CAD higher glycated hemoglobin HbA1c, and smoking.	Cholesterol	110-121	insulin like growth factor binding protein 3	Homo sapiens	12-56	
34239560-10	2021	In addition, total IGFBP-3 levels were positively correlated with total cholesterol and low-density lipoprotein cholesterol and IGF-I levels but not with age or body mass index.	Cholesterol	72-83	insulin like growth factor binding protein 3	Homo sapiens	19-26	
9225724-8	1997	Finally, serum levels of IGFBP-3, but not those of IGF-I, were positively correlated with serum levels of total cholesterol and triglyceride.	Cholesterol	112-123	insulin like growth factor binding protein 3	Homo sapiens	25-32	
34161114-5	2021	IGFBP-3 was in positive correlation with total cholesterol (p=0.026), LDL cholesterol (p=0.03) and triacylglycerols (p=0.022).	Cholesterol	47-58	insulin like growth factor binding protein 3	Homo sapiens	0-7	
34161114-5	2021	IGFBP-3 was in positive correlation with total cholesterol (p=0.026), LDL cholesterol (p=0.03) and triacylglycerols (p=0.022).	Cholesterol	74-85	insulin like growth factor binding protein 3	Homo sapiens	0-7	
32410151-13	2020	(3) In females, the change in IGFBP3 level was associated with a change in high-density lipoprotein cholesterol and free fatty acid levels (r = 0.607, P = 0.003; r = 0.546, P = 0.016), and a change in total IGF1 level was associated with a change in CRP level (r = 0.664, P = 0.009).	Cholesterol	100-111	insulin like growth factor binding protein 3	Homo sapiens	30-36