PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17214991-0 2007 SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. Cholesterol 78-89 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 0-5 21145937-0 2011 Tyrosine phosphatases as key regulators of StAR induction and cholesterol transport: SHP2 as a potential tyrosine phosphatase involved in steroid synthesis. Cholesterol 62-73 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 85-89 17214991-0 2007 SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. Cholesterol 78-89 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 27-33 17214991-3 2007 We hypothesized that variants in the SHP-2 gene PTPN11 and PI3K p85alpha subunit gene PIK3R1 may influence fasting levels of plasma apoB and/or LDL cholesterol. Cholesterol 148-159 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 37-42 17214991-3 2007 We hypothesized that variants in the SHP-2 gene PTPN11 and PI3K p85alpha subunit gene PIK3R1 may influence fasting levels of plasma apoB and/or LDL cholesterol. Cholesterol 148-159 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 48-54 17214991-7 2007 PTPN11 tSNP rs11066322 interacted with PIK3R1 tSNP rs251406 in determining serum apoB levels (P=0.012) and with PIK3R1 tSNP rs40318 in determining LDL cholesterol levels (P=0.009). Cholesterol 151-162 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 0-6 17214991-8 2007 Association of single tSNPs with both apoB and LDL cholesterol as well as interactions between the two genes suggest that variants influencing SHP-2 activity may modulate the acute pathway by which insulin regulates these lipids. Cholesterol 51-62 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 143-148 33382187-12 2021 Moreover, women with PTPN11 mutations had lower HDL-cholesterol levels than those without. Cholesterol 52-63 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 21-27 12611902-0 2003 Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism. Cholesterol 56-67 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 18-23 12611902-4 2003 We find that as endothelial cells reach confluence, the tyrosine phosphatase SHP-2 is recruited to a low-density membrane fraction in a cholesterol-dependent manner. Cholesterol 136-147 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 77-82