PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30220454-3	2018	We now show that caspase-2, whose expression is ER-stress inducible and elevated in human and mouse NASH, controls the buildup of hepatic-free cholesterol and triglycerides by activating sterol regulatory element-binding proteins (SREBP) in a manner refractory to feedback inhibition.	Cholesterol	143-154	caspase 2	Homo sapiens	17-26	
25330190-4	2014	Silencing of caspase-2 expression in cultured glioblastoma cells allows the up-regulation of a limited number of genes, among which some are related to cholesterol homeostasis.	Cholesterol	152-163	caspase 2	Homo sapiens	13-22	
25330190-5	2014	Lysosomal Acid Lipase A (LIPA) was up-regulated in two different cell lines in response to caspase-2 down-regulation and cells silenced for caspase-2 exhibit reduced cholesterol staining in the lipid droplets.	Cholesterol	166-177	caspase 2	Homo sapiens	140-149	
25330190-8	2014	In the brain, hierarchical clustering has revealed that the expression of regulative apoptotic caspases (CASP2, CASP8 CASP9, CASP10) and of the inflammatory CASP1 is linked to several genes involved in cholesterol homeostasis.	Cholesterol	202-213	caspase 2	Homo sapiens	105-110	
16227610-6	2005	Taken together, our results identify the human CASP-2 gene as a member of the SREBP-responsive gene battery that senses lipid levels in cells and raise the possibility that caspase-2 participates in the control of cholesterol and triacylglycerol levels.	Cholesterol	214-225	caspase 2	Homo sapiens	47-53	
16227610-6	2005	Taken together, our results identify the human CASP-2 gene as a member of the SREBP-responsive gene battery that senses lipid levels in cells and raise the possibility that caspase-2 participates in the control of cholesterol and triacylglycerol levels.	Cholesterol	214-225	caspase 2	Homo sapiens	173-182