PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33890572-5	2021	Together with quantitative cell biology approaches, the screen reveals an essential role for biophysical aspects of the membrane, particularly cholesterol-rich regions, in spike-mediated fusion, which extends to replication-competent SARS-CoV-2 isolates.	Cholesterol	143-154	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	172-177	
33239446-3	2020	Internalized 25HC accumulates in the late endosomes and potentially restricts SARS-CoV-2 spike protein catalyzed membrane fusion via blockade of cholesterol export.	Cholesterol	145-156	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	89-94	
34157514-4	2021	Here we demonstrate that the SARS-CoV-2 spike (S) protein interferes with the function of lipoproteins, and that this is dependent on cholesterol.	Cholesterol	134-145	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	40-45	
34157514-4	2021	Here we demonstrate that the SARS-CoV-2 spike (S) protein interferes with the function of lipoproteins, and that this is dependent on cholesterol.	Cholesterol	134-145	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	47-48	
34157514-6	2021	Additionally, the S protein removes lipids and cholesterol from model membranes.	Cholesterol	47-58	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	18-19	
34522180-5	2021	Previous studies have shown that the fusion protein of the virus interacts with cholesterol, and the spike protein of SARS-CoV-2 also requires cholesterol to enter the host cells.	Cholesterol	143-154	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	101-106	
34522180-6	2021	Cholesterol in blood interacts with the spike protein to promote the entry of spike cells, wherein the scavenger receptor class B type 1 (SR-B1) plays an important role.	Cholesterol	0-11	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	40-45	
34522180-6	2021	Cholesterol in blood interacts with the spike protein to promote the entry of spike cells, wherein the scavenger receptor class B type 1 (SR-B1) plays an important role.	Cholesterol	0-11	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	78-83	
35547841-4	2022	With examples of zwitterionic dipalmitoyl phosphatidyl choline, cholesterol, and anionic sodium dodecyl sulphate, we show that surfactants form micellar aggregates that selectively adhere to the specific regions of S1 domain of the Spike protein that are responsible for binding with ACE2 receptors and virus transmission into the cells.	Cholesterol	64-75	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	232-237