PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19122179-4	2009	In mechanistic studies, cholesterol loading of macrophage plasma membranes (cyclodextrin-cholesterol) or endosomal system (AcLDL+U18666A or Npc1 null mutation) activated Toll-like receptor (TLR) signaling, leading to sustained phosphorylation of p38 mitogen-activated protein kinase and induction of p38 targets, including Ctsk, S100a8, Mmp8, and Mmp14.	Cholesterol	24-35	S100 calcium binding protein A8 (calgranulin A)	Mus musculus	329-335	
19122179-7	2009	These studies suggest that free cholesterol enrichment of either plasma or endosomal membranes in macrophages leads to activation of signaling via various TLRs, prolonged p38 mitogen-activated protein kinase activation, and induction of Mmps, Ctsk, and S100a8, potentially contributing to plaque complications.	Cholesterol	32-43	S100 calcium binding protein A8 (calgranulin A)	Mus musculus	253-259	
34449045-0	2021	Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration.	Cholesterol	112-123	S100 calcium binding protein A8 (calgranulin A)	Mus musculus	56-62	
34449045-8	2021	We report that a high-fat/high-cholesterol diet leads to an increase in S100A8 production in the brain.	Cholesterol	31-42	S100 calcium binding protein A8 (calgranulin A)	Mus musculus	72-78