PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33843209-12	2021	NSC23766, a specific inhibitor of Rac1, fully abolished harmful effects of MEG3 depletion.	NSC 23766	0-8	Rac family small GTPase 1	Rattus norvegicus	34-38	
35083636-12	2022	However, Rac1 inhibitor NSC23766 could have effectively reversed ketamine-mediated changes in the hippocampus of rats and counteracted its antidepressant effects.	NSC 23766	24-32	Rac family small GTPase 1	Rattus norvegicus	9-13	
32040269-0	2020	Inhibition of Rac1 activity by NSC23766 prevents cartilage endplate degeneration via Wnt/beta-catenin pathway.	NSC 23766	31-39	Rac family small GTPase 1	Rattus norvegicus	14-18	
33081375-8	2020	Moreover, the Rac1 inhibitor NSC23766 prevented Y-27632-induced AKT and p21-activated kinase 1 (PAK1) activation.	NSC 23766	29-37	Rac family small GTPase 1	Rattus norvegicus	14-18	
32641997-10	2020	In the IL, Rac1 signaling was increased during withdrawal, and the Rac1 inhibitor NSC23766 disrupted SK current, which increased neuronal firing.	NSC 23766	82-90	Rac family small GTPase 1	Rattus norvegicus	67-71	
32040269-6	2020	Our study revealed that Rac1 inhibitor NSC23766 treatment promoted the expression of collagen II, aggrecan and Sox-9, and decreased the expression of ADTAMTS5 and MMP13 in IL-1beta-stimulated rat EPCs.	NSC 23766	39-47	Rac family small GTPase 1	Rattus norvegicus	24-28	
32040269-7	2020	Moreover, we also found that NSC23766 could suppress the activation of Wnt/beta-catenin pathway, suggesting that the beneficial effects of Rac1 inhibition in EPCs are mediated through the Wnt/beta-catenin signalling.	NSC 23766	29-37	Rac family small GTPase 1	Rattus norvegicus	139-143	
33405734-6	2019	For in vivo evaluation, we further developed a drug delivery system to encapsulate Rac1 inhibitor NSC23766.	NSC 23766	98-106	Rac family small GTPase 1	Rattus norvegicus	83-87	
25319697-0	2014	The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function.	NSC 23766	19-27	Rac family small GTPase 1	Rattus norvegicus	4-8