PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19652385-5 2009 Furthermore, this study showed that amentoflavone, at a concentration greater than 75 microM, increased the cleavage-activity of caspase-3 and poly (ADP-ribose) polymerase (PARP), and administration of pan-caspase inhibitor Z-VAD-FMK completely rescued the SK-BR-3 cells from PARP cleavages. amentoflavone 36-49 poly(ADP-ribose) polymerase 1 Homo sapiens 173-177 21663495-7 2011 Furthermore, amentoflavone treatment led to the activation of caspase-3 and -9 and proteolytic cleavage of poly(ADP-ribose) polymerase. amentoflavone 13-26 poly(ADP-ribose) polymerase 1 Homo sapiens 107-134 30466996-0 2018 Identification of amentoflavone as a potent highly selective PARP-1 inhibitor and its potentiation on carboplatin in human non-small cell lung cancer. amentoflavone 18-31 poly(ADP-ribose) polymerase 1 Homo sapiens 61-67 30466996-2 2018 This study first investigated the inhibitory effects of amentoflavone (AMF) and its derivatives on PARP-1 and the potentiation of AMF on carboplatin (CBP) in non-small cell lung cancer (NSCLC). amentoflavone 56-69 poly(ADP-ribose) polymerase 1 Homo sapiens 99-105 30466996-2 2018 This study first investigated the inhibitory effects of amentoflavone (AMF) and its derivatives on PARP-1 and the potentiation of AMF on carboplatin (CBP) in non-small cell lung cancer (NSCLC). amentoflavone 71-74 poly(ADP-ribose) polymerase 1 Homo sapiens 99-105 19652385-5 2009 Furthermore, this study showed that amentoflavone, at a concentration greater than 75 microM, increased the cleavage-activity of caspase-3 and poly (ADP-ribose) polymerase (PARP), and administration of pan-caspase inhibitor Z-VAD-FMK completely rescued the SK-BR-3 cells from PARP cleavages. amentoflavone 36-49 poly(ADP-ribose) polymerase 1 Homo sapiens 276-280 34404206-2 2021 Amentoflavone (AMF) is reported to be a selective PARP-1 inhibitor. amentoflavone 0-13 poly(ADP-ribose) polymerase 1 Homo sapiens 50-56 34404206-2 2021 Amentoflavone (AMF) is reported to be a selective PARP-1 inhibitor. amentoflavone 15-18 poly(ADP-ribose) polymerase 1 Homo sapiens 50-56