PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32962858-7 2020 Compared to monotherapy, combined treatment of glioma cells with PLK1 and STAT3 inhibitors, BI2536 and Stattic, respectively, showed lower expression of MYC, synergistic induction of cell invasion and apoptosis in vitro, and tumor inhibition in xenografts. BI 2536 92-98 MYC proto-oncogene, bHLH transcription factor Homo sapiens 153-156 34376582-6 2021 In addition, ISQ-1 treatment showed remarkable synergistic depletion of oncogenic c-Myc protein level in vitro and induced strong tumor remission in vivo when administered together with BI2536, a polo-like kinase-1 (Plk1) inhibitor. BI 2536 186-192 MYC proto-oncogene, bHLH transcription factor Homo sapiens 82-87