PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24525736-5 2014 Treatment of hepatoma cells with salubrinal, an inhibitor of eIF2alpha dephosphorylation, enhances TRAIL-induced eIF2alpha phosphorylation, CCAAT/enhancer-binding protein homologous protein (CHOP) expression and caspase activation. salubrinal 33-43 TNF superfamily member 10 Homo sapiens 99-104 24525736-6 2014 Salubrinal enhances TRAIL-induced apoptosis, which could be abrogated by caspase inhibitor. salubrinal 0-10 TNF superfamily member 10 Homo sapiens 20-25 24525736-8 2014 By contrast, overexpression of phosphodeficient eIF2alpha (S51A) abrogates the stimulation of TRAIL-induced apoptosis by salubrinal. salubrinal 121-131 TNF superfamily member 10 Homo sapiens 94-99 24525736-10 2014 Furthermore, the sensitization of hepatoma cells to TRAIL by salubrinal is dependent on CHOP. salubrinal 61-71 TNF superfamily member 10 Homo sapiens 52-57 24525736-11 2014 Knockdown of CHOP abrogates the stimulation of TRAIL-induced caspase activation and apoptosis by salubrinal. salubrinal 97-107 TNF superfamily member 10 Homo sapiens 47-52 24525736-13 2014 Bim knockdown blunts the stimulatory effect of salubrinal on TRAIL-induced apoptosis. salubrinal 47-57 TNF superfamily member 10 Homo sapiens 61-66 21660448-10 2012 Furthermore, DMF-mediated sensitization of HCC cells to TRAIL was reduced by administration of a blocking antibody or small interfering RNAs for DR5, salubrinal, an inhibitor of ER stress, and the small interfering RNAs for CHOP. salubrinal 150-160 TNF superfamily member 10 Homo sapiens 56-61