PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30718413-0	2019	DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis.	Vitamin A	15-22	diacylglycerol O-acyltransferase 1	Homo sapiens	0-5	
6516908-1	1984	Recent work has shown that esterification of retinol in microsomes from rat liver, mammary gland and small intestine and from human small intestine is catalyzed by an acyl CoA: retinol acyl transferase (ARAT).	Vitamin A	45-52	diacylglycerol O-acyltransferase 1	Homo sapiens	167-201	
6516908-1	1984	Recent work has shown that esterification of retinol in microsomes from rat liver, mammary gland and small intestine and from human small intestine is catalyzed by an acyl CoA: retinol acyl transferase (ARAT).	Vitamin A	45-52	diacylglycerol O-acyltransferase 1	Homo sapiens	203-207	
30718413-4	2019	DGAT1 acyltransferase activity sequesters retinol in ester form, preventing synthesis of retinoic acid, a cofactor for Treg generation.	Vitamin A	42-49	diacylglycerol O-acyltransferase 1	Homo sapiens	0-5	
30718413-5	2019	In cultures with T cell-depleted lymphoid tissues, retinol enhanced Treg induction from DGAT1-/- but not from WT T cells.	Vitamin A	51-58	diacylglycerol O-acyltransferase 1	Homo sapiens	88-93	
30718413-7	2019	These results demonstrate that DGAT1 suppresses retinol-dependent Treg formation and suggest its potential as a therapeutic target for autoimmune inflammation.	Vitamin A	48-55	diacylglycerol O-acyltransferase 1	Homo sapiens	31-36	
23558010-4	2013	Following a single dose of a selective pharmacological inhibitor of DGAT1, PF-04620110, a dose-dependent inhibition of TG and vitamin A absorption postprandially was demonstrated in rodents and human subjects.	Vitamin A	126-135	diacylglycerol O-acyltransferase 1	Homo sapiens	68-73	
16214399-3	2005	The apparent K(m) values of recombinant DGAT1/ARAT for retinol and palmitoyl coenzyme A were determined to be 25.9+/-2.1 microM and 13.9+/-0.3 microM, respectively, both of which are similar to the values previously determined for ARAT in native tissues.	Vitamin A	55-62	diacylglycerol O-acyltransferase 1	Homo sapiens	40-45	
16214399-3	2005	The apparent K(m) values of recombinant DGAT1/ARAT for retinol and palmitoyl coenzyme A were determined to be 25.9+/-2.1 microM and 13.9+/-0.3 microM, respectively, both of which are similar to the values previously determined for ARAT in native tissues.	Vitamin A	55-62	diacylglycerol O-acyltransferase 1	Homo sapiens	46-50	
16214399-3	2005	The apparent K(m) values of recombinant DGAT1/ARAT for retinol and palmitoyl coenzyme A were determined to be 25.9+/-2.1 microM and 13.9+/-0.3 microM, respectively, both of which are similar to the values previously determined for ARAT in native tissues.	Vitamin A	55-62	diacylglycerol O-acyltransferase 1	Homo sapiens	231-235	
16214399-4	2005	A novel selective DGAT1 inhibitor, XP620, inhibits recombinant DGAT1/ARAT at the retinol recognition site.	Vitamin A	81-88	diacylglycerol O-acyltransferase 1	Homo sapiens	18-23	
16214399-4	2005	A novel selective DGAT1 inhibitor, XP620, inhibits recombinant DGAT1/ARAT at the retinol recognition site.	Vitamin A	81-88	diacylglycerol O-acyltransferase 1	Homo sapiens	63-68	
16214399-4	2005	A novel selective DGAT1 inhibitor, XP620, inhibits recombinant DGAT1/ARAT at the retinol recognition site.	Vitamin A	81-88	diacylglycerol O-acyltransferase 1	Homo sapiens	69-73