PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16647258-1 2006 The preparation of the sulfoxide analogues 7, 8, and 9 and their enantiomerically pure forms is discussed as well as their ability to act as prodrugs of the potent and selective sulfone-containing COX-2 inhibitors 1, 2, and 3. Sulfones 178-185 cytochrome c oxidase II, mitochondrial Rattus norvegicus 197-202 16616494-1 2006 The preparation of the sulfoxide analogues 2 and 4, and their enantiomeric pure forms is discussed as well as their potential to act as prodrugs to the potent and selective sulfone-containing COX-2 inhibitors rofecoxib and etoricoxib. Sulfones 173-180 cytochrome c oxidase II, mitochondrial Rattus norvegicus 192-197