PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28094278-1 2017 Secondary hyperparathyroidism, in which parathyroid hormone (PTH) is excessively secreted in response to factors such as hyperphosphataemia, hypocalcaemia, and low 1,25-dihydroxyvitamin D (1,25(OH)2D) levels, is commonly observed in patients with chronic kidney disease (CKD), and is accompanied by high levels of fibroblast growth factor 23 (FGF23). 25-dihydroxyvitamin d 166-187 parathyroid hormone Homo sapiens 40-59 27927781-6 2017 We discovered associations of SNPs from five independent regions with serum PTH concentration, including the strongest association with rs6127099 upstream of CYP24A1 (P=4.2 x 10-53), a gene that encodes the primary catabolic enzyme for 1,25-dihydroxyvitamin D and 25-dihydroxyvitamin D. 25-dihydroxyvitamin d 238-259 parathyroid hormone Homo sapiens 76-79 28094278-1 2017 Secondary hyperparathyroidism, in which parathyroid hormone (PTH) is excessively secreted in response to factors such as hyperphosphataemia, hypocalcaemia, and low 1,25-dihydroxyvitamin D (1,25(OH)2D) levels, is commonly observed in patients with chronic kidney disease (CKD), and is accompanied by high levels of fibroblast growth factor 23 (FGF23). 25-dihydroxyvitamin d 166-187 parathyroid hormone Homo sapiens 61-64 23652554-2 2013 In patients with chronic kidney disease (CKD), circulating levels of parathyroid hormone (PTH) are progressively increased as kidney function declines, as a result of phosphate retention, hypocalcemia, decreased production of 1,25-dihydroxyvitamin D [1,25(OH)2D], endogenous changes within the parathyroid gland, and skeletal resistance to the actions of PTH. 25-dihydroxyvitamin d 228-249 parathyroid hormone Homo sapiens 69-88