PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17049224-4 2006 First, substantial advances have been made in the development of inhibitors based on immunophilin ligand polyketides, which target the TOR-mediated pathways and can modulate processes including cell proliferation and cell-cycle arrest. Polyketides 105-116 RAR related orphan receptor C Homo sapiens 135-138