PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22229794-4 2012 Covalent tethering of the 2-methyl-3-ketobutyryl thioester substrate to the NANS ACP1 domain derived from the natural upstream PKS module of the nanchangmycin synthase significantly enhanced both the stereospecificity and the kinetic efficiency of the sequential polyketide chain translocation and condensation reactions catalyzed by the ketosynthase domain of NANS module 2. Polyketides 263-273 acid phosphatase 1 Homo sapiens 81-85