PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12183690-1 2002 The polyketides FK506 (tacrolimus) and FK520 (ascomycin) are potent immunosuppressants that function by inhibiting calcineurin phosphatase through formation of an FKBP12-FK506/520-calcineurin ternary complex. Polyketides 4-15 FKBP prolyl isomerase 1A Rattus norvegicus 163-169