PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17620609-5 2007 Using rounds of mutagenesis coupled with in vivo screens for NRP production, we rapidly isolated variants of two different chimeric NRPSs with approximately 10-fold improvements in enzyme activity and product yield, including one that produces new derivatives of the potent NRP/polyketide antibiotic andrimid. Polyketides 278-288 neuropilin 1 Homo sapiens 61-64 17620609-5 2007 Using rounds of mutagenesis coupled with in vivo screens for NRP production, we rapidly isolated variants of two different chimeric NRPSs with approximately 10-fold improvements in enzyme activity and product yield, including one that produces new derivatives of the potent NRP/polyketide antibiotic andrimid. Polyketides 278-288 neuropilin 1 Homo sapiens 132-135