PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14973242-5 2004 In cell culture experiments, S1627 inhibited interleukin (IL)-1beta-stimulated nuclear translocation and DNA-binding of NF-kappaB. nitazoxanide 29-34 interleukin 1 beta Rattus norvegicus 45-67 14973242-11 2004 As hypothesized, S1627 prevented the zymosan-induced nuclear translocation of NF-kappaB in the spinal cord and the upregulation of NF-kappaB-responsive genes including cyclooxygenase-2, tumor necrosis factor-alpha, and IL-1beta. nitazoxanide 17-22 interleukin 1 beta Rattus norvegicus 219-227