PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35391601-0 2022 Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence. nitazoxanide 78-90 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 25-30 35391601-4 2022 Here, we demonstrate that nitazoxanide, an antiprotozoal agent with recognized broad-spectrum antiviral activity, interferes with SARS-CoV-2 spike maturation, hampering its terminal glycosylation at an endoglycosidase H-sensitive stage. nitazoxanide 26-38 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 141-146 35391601-6 2022 Nitazoxanide, being equally effective against the ancestral SARS-CoV-2 Wuhan-spike and different emerging variants, including the Delta variant of concern, may represent a useful tool in the fight against COVID-19 infections. nitazoxanide 0-12 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 77-82