PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33741556-10 2021 CONCLUSION: Filgotinib inhibited JAK1-mediated signalling similarly to other JAKinibs, but with less inhibition of JAK2-dependent and JAK3-dependent pathways, providing a mechanistic rationale for its apparently differentiated efficacy:safety profile. GLPG0634 12-22 Janus kinase 3 Homo sapiens 134-138