PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24552773-7	2014	Furthermore, ponatinib abrogated the phosphorylation of beta-catenin at the site Y654, suppressed the translocation of beta-catenin, and inhibited the transcription and DNA binding of TCF and the expression of its targets (e.g., AXIN2, c-MYC, and CCND1).	ponatinib	13-22	cyclin D1	Homo sapiens	247-252	
30959969-3	2019	Toward SK-Hep-1 and SNU-423 cells, ponatinib induces apoptosis by upregulation of cleaved caspase-3 and -7 and promotes cell cycle arrest in the G1 phase by inhibiting CDK4/6/CyclinD1 complex and phosphorylation of retinoblastoma protein.	ponatinib	35-44	cyclin D1	Homo sapiens	175-183