PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15665588-4	2004	JNK inhibitor, SP600125,markedly inhibited pseudolaric acid B-induced celldeath.	pseudolaric acid B	43-61	mitogen-activated protein kinase 8	Homo sapiens	0-3	
18718176-0	2008	Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells.	pseudolaric acid B	53-71	mitogen-activated protein kinase 8	Homo sapiens	25-28	
18718176-5	2008	P38 had no obvious function on apoptosis after 4 micromol/L PAB treatment for 36 h, but PAB induced JNK phosphorylation and inhibited ERK phosphorylation in the apoptotic process.	pseudolaric acid B	88-91	mitogen-activated protein kinase 8	Homo sapiens	100-103	
18718176-8	2008	Together with PAB, genistein increased the expression of p-ERK, and decreased the expressions of JNK and p-JNK in PAB-treated MCF-7 cells at 36 h. And it is considered that the p-ERK and p-JNK were active patterns of ERK and JNK, respectively.	pseudolaric acid B	114-117	mitogen-activated protein kinase 8	Homo sapiens	97-100	
18718176-8	2008	Together with PAB, genistein increased the expression of p-ERK, and decreased the expressions of JNK and p-JNK in PAB-treated MCF-7 cells at 36 h. And it is considered that the p-ERK and p-JNK were active patterns of ERK and JNK, respectively.	pseudolaric acid B	114-117	mitogen-activated protein kinase 8	Homo sapiens	107-110	
18718176-8	2008	Together with PAB, genistein increased the expression of p-ERK, and decreased the expressions of JNK and p-JNK in PAB-treated MCF-7 cells at 36 h. And it is considered that the p-ERK and p-JNK were active patterns of ERK and JNK, respectively.	pseudolaric acid B	114-117	mitogen-activated protein kinase 8	Homo sapiens	107-110	
18718176-8	2008	Together with PAB, genistein increased the expression of p-ERK, and decreased the expressions of JNK and p-JNK in PAB-treated MCF-7 cells at 36 h. And it is considered that the p-ERK and p-JNK were active patterns of ERK and JNK, respectively.	pseudolaric acid B	114-117	mitogen-activated protein kinase 8	Homo sapiens	107-110	
18718176-9	2008	CONCLUSION: PTK were upstream of ERK and JNK, and PTK induced apoptosis through activating JNK and inactivating ERK in PAB-treated MCF-7 cells.	pseudolaric acid B	119-122	mitogen-activated protein kinase 8	Homo sapiens	41-44	
16953122-0	2006	Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death.	pseudolaric acid B	76-94	mitogen-activated protein kinase 8	Homo sapiens	15-18