PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22406864-0	2012	Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model.	pseudolaric acid B	0-18	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	45-50	
22406864-1	2012	We have recently discovered that c-Jun executes a non-transcriptional function to stabilize hypoxia inducible factor 1alpha (HIF-1alpha) and that pseudolaric acid B (PAB) accelerates HIF-1alpha degradation and phosphorylates c-Jun at Ser63/73.	pseudolaric acid B	146-164	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	225-230	
22406864-1	2012	We have recently discovered that c-Jun executes a non-transcriptional function to stabilize hypoxia inducible factor 1alpha (HIF-1alpha) and that pseudolaric acid B (PAB) accelerates HIF-1alpha degradation and phosphorylates c-Jun at Ser63/73.	pseudolaric acid B	166-169	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	225-230	
22406864-4	2012	However, c-Jun siRNA, which reduced both the PAB-driven phosphorylated c-Jun and the total c-Jun protein, did not prevent the PAB-induced decrease in HIF-1alpha.	pseudolaric acid B	45-48	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	9-14	
22406864-4	2012	However, c-Jun siRNA, which reduced both the PAB-driven phosphorylated c-Jun and the total c-Jun protein, did not prevent the PAB-induced decrease in HIF-1alpha.	pseudolaric acid B	45-48	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	71-76	
22406864-4	2012	However, c-Jun siRNA, which reduced both the PAB-driven phosphorylated c-Jun and the total c-Jun protein, did not prevent the PAB-induced decrease in HIF-1alpha.	pseudolaric acid B	45-48	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	71-76	
22406864-6	2012	PAB increased the phosphorylated c-Jun while reducing the non-phosphorylated c-Jun at Ser63/73, which impaired its function in stabilizing HIF-1alpha.	pseudolaric acid B	0-3	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	33-38	
22406864-6	2012	PAB increased the phosphorylated c-Jun while reducing the non-phosphorylated c-Jun at Ser63/73, which impaired its function in stabilizing HIF-1alpha.	pseudolaric acid B	0-3	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	77-82	
22922347-5	2012	In particular, through studies on the antiangiogenic mechanism of pseudolaric acid B, we discovered a novel mechanism by which the stability of hypoxia-inducible factor 1alpha is regulated by the transcription factor c-Jun.	pseudolaric acid B	66-84	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	217-222