PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25749779-3 2015 The aims of this study were to examine the inhibitory effect of delphinidin on TGF-beta1-induced myofibroblast differentiation and ECM accumulation, and to determine the underlying mechanisms in nasal polyp-derived fibroblasts (NPDFs). delphinidin 64-75 transforming growth factor beta 1 Homo sapiens 79-88 27649384-7 2017 Dp was the most potent EMT inhibitor through its inhibitory effect on the TGF-beta Smad and non-Smad signaling pathways. delphinidin 0-2 transforming growth factor beta 1 Homo sapiens 74-82 30365941-0 2019 Delphinidin protects beta2m-/Thy1+ bone marrow-derived hepatocyte stem cells against TGF-beta1-induced oxidative stress and apoptosis through the PI3K/Akt pathway in vitro. delphinidin 0-11 transforming growth factor beta 1 Homo sapiens 85-94 30365941-7 2019 In the present research, we determined whether delphinidin pretreatment can improve the survival of beta2m-/Thy1+ BDHSCs during exposure to TGF-beta1 and elucidated its underlying mechanisms. delphinidin 47-58 transforming growth factor beta 1 Homo sapiens 140-149 30365941-11 2019 We found that delphinidin can significantly impede TGF-beta1-induced apoptosis dose-dependently, scavenge reactive oxygen species (ROS), and inhibit the discharge of caspase-3 in beta2m-/Thy1+ BDHSCs. delphinidin 14-25 transforming growth factor beta 1 Homo sapiens 51-60 30365941-14 2019 In summary, our findings revealed that delphinidin can protect beta2m-/Thy1+ BDHSCs from apoptosis and ROS-dependent oxidative stress induced by the TGF-beta1 via PI3K/Akt signaling pathway. delphinidin 39-50 transforming growth factor beta 1 Homo sapiens 149-158 25749779-9 2015 In TGF-beta1-induced NPDFs, delphinidin inhibited the expression of alpha-SMA, fibronectin, and collagen. delphinidin 28-39 transforming growth factor beta 1 Homo sapiens 3-12 25749779-11 2015 Delphinidin suppressed the activation of MAPK and NF-kappaB induced by TGF-beta1 stimulation. delphinidin 0-11 transforming growth factor beta 1 Homo sapiens 71-80 25749779-12 2015 CONCLUSIONS: These results suggest that delphinidin may inhibit TGF-beta1-induced myofibroblast differentiation and ECM production through the MAPK/NF-kappaB signaling pathway in NPDFs. delphinidin 40-51 transforming growth factor beta 1 Homo sapiens 64-73