PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20969858-3 2011 However, it is unknown whether neferine also has an inhibitory effect on liver fibrosis through inhibition of TGF-beta1 and collagen I and facilitation of apoptosis of hepatic stellate cells. neferine 31-39 transforming growth factor, beta 1 Rattus norvegicus 110-119 20969858-5 2011 The results showed that neferine administration (2, 4, 6, 8 and 10mumol/l) significantly decreased the TGF-beta1 and collagen I produced in HSC-T6 cells, and increased the HSC-T6 cell apoptosis in a dose-dependent manner. neferine 24-32 transforming growth factor, beta 1 Rattus norvegicus 103-112 35347819-9 2022 Pretreatment with neferine markedly activated SIRT1 expression and modulated the expression levels of TGF-beta1 and p53, thereby significantly reducing DOX-induced fibrosis, hypertrophy, and apoptosis in H9c2 cardiomyoblasts. neferine 18-26 transforming growth factor, beta 1 Rattus norvegicus 102-111 33680053-7 2021 Neferine also decreased the levels of alpha-smooth muscle actin (alpha-SMA), transforming growth factor beta1 (TGF-beta1), and inflammatory factors. neferine 0-8 transforming growth factor, beta 1 Rattus norvegicus 77-109 33680053-7 2021 Neferine also decreased the levels of alpha-smooth muscle actin (alpha-SMA), transforming growth factor beta1 (TGF-beta1), and inflammatory factors. neferine 0-8 transforming growth factor, beta 1 Rattus norvegicus 111-120