PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28700977-6	2017	Hypoxia-induced Tumor Necrosis Factor-alpha (TNF-alpha), Interleukin 6 (IL-6), and Interleukin 8 (IL-8) release were significantly reduced in the neferine pretreated samples indicating its anti-inflammatory role.	neferine	146-154	tumor necrosis factor	Homo sapiens	16-43	
28700977-6	2017	Hypoxia-induced Tumor Necrosis Factor-alpha (TNF-alpha), Interleukin 6 (IL-6), and Interleukin 8 (IL-8) release were significantly reduced in the neferine pretreated samples indicating its anti-inflammatory role.	neferine	146-154	tumor necrosis factor	Homo sapiens	45-54	
34361003-9	2021	Through in vitro studies, we found that neferine inhibited the expression of cytokines and chemokines in TNF-alpha/IFN-gamma-stimulated human keratinocyte (HaCaT) cells, and it reduced the phosphorylation of MAPK and the NF-kappaB signaling pathway.	neferine	40-48	tumor necrosis factor	Homo sapiens	105-114	
23122111-7	2013	In addition, expression levels of TNF-alpha, p38 and ERK1/2 MAP kinases were increased upon neferine treatment.	neferine	92-100	tumor necrosis factor	Homo sapiens	34-43