PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7545393-5 1995 We show that pyrrolidine dithiocarbamate strongly reduces the TNF alpha-mediated induction of E-selectin, VCAM-1, ICAM-1, PAI-1, tissue factor, IL-8 and I kappa B-alpha. pyrrolidine dithiocarbamic acid 13-40 selectin E Homo sapiens 94-104 9728048-3 1998 Pretreatment with N-acetyl-L-cysteine (NAC) or pyrrolidine dithiocarbamate (PDTC) for 0.5 h inhibited TNF-alpha-induced generation of ROS as well as activation of NF-kappaB and E-selectin mRNA and the cell surface protein expression. pyrrolidine dithiocarbamic acid 47-74 selectin E Homo sapiens 177-187 9728048-3 1998 Pretreatment with N-acetyl-L-cysteine (NAC) or pyrrolidine dithiocarbamate (PDTC) for 0.5 h inhibited TNF-alpha-induced generation of ROS as well as activation of NF-kappaB and E-selectin mRNA and the cell surface protein expression. pyrrolidine dithiocarbamic acid 76-80 selectin E Homo sapiens 177-187 9048649-10 1997 Induction of E-selectin mRNA by lipopolysaccharide or TNF-alpha in cycloheximide-treated HASMCs was inhibited by the antioxidant pyrrolidinedithiocarbamate and the serine protease inhibitor N alpha-L-tosyl-L-phenylalanine chloromethyl ketone, suggesting that a nuclear factor-kappa B-like mechanism may play an important role in E-selectin gene expression in HASMCs. pyrrolidine dithiocarbamic acid 129-155 selectin E Homo sapiens 13-23 9048649-10 1997 Induction of E-selectin mRNA by lipopolysaccharide or TNF-alpha in cycloheximide-treated HASMCs was inhibited by the antioxidant pyrrolidinedithiocarbamate and the serine protease inhibitor N alpha-L-tosyl-L-phenylalanine chloromethyl ketone, suggesting that a nuclear factor-kappa B-like mechanism may play an important role in E-selectin gene expression in HASMCs. pyrrolidine dithiocarbamic acid 129-155 selectin E Homo sapiens 329-339