PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14984805-2	2004	Before the administration of formalin, NPY dose dependently increased blood pressure, an effect that could be prevented with the coadministration of the Y2 antagonist, BIIE0246.	BIIE 0246	168-176	neuropeptide Y	Rattus norvegicus	39-42	
17976913-9	2008	NPY inhibition of SNI-induced Fos expression was localized to the sural (uninjured) innervation territory, and could be blocked by intrathecal BIBO3304 and BIIE0246.	BIIE 0246	156-164	neuropeptide Y	Rattus norvegicus	0-3	
16081487-9	2005	In addition, compared to baseline, BIIE0246 infusion resulted in increased plasma neuropeptide Y concentration in females (P < 0.05), while there was no observable change in males.	BIIE 0246	35-43	neuropeptide Y	Rattus norvegicus	82-96	
15927700-8	2005	The enhancement of the NPY induced increase in DOPA accumulation observed by BIBO3304 was attenuated when examined in the presence of the Y2 antagonist BIIE0246.	BIIE 0246	152-160	neuropeptide Y	Rattus norvegicus	23-26	
18005069-6	2007	NPY was administered intracerebroventricularly, intrahippocampally via the microdialysis probe, or coadministered intrahippocampally with the D2 receptor antagonist remoxipride, the Y2 receptor antagonist BIIE0246 or the sigma 1 receptor antagonist BD1047.	BIIE 0246	205-213	neuropeptide Y	Rattus norvegicus	0-3	
18005069-10	2007	Y2 receptor blockade (1 microm BIIE0246) reversed the anticonvulsant effect of NPY but did not prevent NPY-induced increases in hippocampal dopamine.	BIIE 0246	31-39	neuropeptide Y	Rattus norvegicus	79-82	
17382974-8	2007	The Y2 antagonist BIIE0246 produced an attenuation of both the NPY and PYY3-36 induced enhancement while the Y1 antagonist BIBO3304 and theY5 antagonist CGP71683A failed to alter the NPY or PYY3-36 induced enhancement.	BIIE 0246	18-26	neuropeptide Y	Rattus norvegicus	63-66	
17143304-11	2007	The Y2 receptor antagonist, BIIE0246, enhanced the inhibitory NPY effects.	BIIE 0246	28-36	neuropeptide Y	Rattus norvegicus	62-65	
29852245-7	2018	This effect was diminished by both Y1 (BIBO3304) and Y2 (BIIE0246) receptor antagonists, indicating that both receptors participate in mediating the antinociceptive effect of NPY.	BIIE 0246	57-65	neuropeptide Y	Rattus norvegicus	175-178	
12855401-11	2003	Pretreatment with the NPY-Y2 receptor antagonist BIIE-0246 (120 pmol) in the PVN had no significant effect.	BIIE 0246	49-58	neuropeptide Y	Rattus norvegicus	22-25	
12377370-4	2002	Here, we examined the effects of a selective NPY-Y2 receptor antagonist, BIIE0246, on operant responding for ethanol in a sweetened solution, or the sweetened solution without ethanol, during 30 min sessions of free choice between the two.	BIIE 0246	73-81	neuropeptide Y	Rattus norvegicus	45-48	
31736656-6	2019	Y2R agonist PYY (3-36) mimicked and Y2R antagonist BIIE0246 abolished the NPY effects in the mPFC.	BIIE 0246	51-59	neuropeptide Y	Rattus norvegicus	74-77	
12623227-2	2003	The KCl-evoked release of glutamate from hippocampal synaptosomes was inhibited by 1 microM NPY and this effect was insensitive to either BIBP3226 (Y1 receptor antagonist) or L-152,804 (Y5 receptor antagonist), but was sensitive to BIIE0246 (Y2 receptor antagonist).	BIIE 0246	232-240	neuropeptide Y	Rattus norvegicus	92-95	
12055128-9	2002	BIIE0246 (100 nM) completely suppressed the actions of NPY and [ahx(5-24)]NPY in this model.	BIIE 0246	0-8	neuropeptide Y	Rattus norvegicus	55-58	
12055128-9	2002	BIIE0246 (100 nM) completely suppressed the actions of NPY and [ahx(5-24)]NPY in this model.	BIIE 0246	0-8	neuropeptide Y	Rattus norvegicus	74-77	
12055128-11	2002	BIIE0246 potently suppresses NPY actions in rat hippocampus, suggesting a dominant role for Y(2)R there.	BIIE 0246	0-8	neuropeptide Y	Rattus norvegicus	29-32	
11934810-8	2002	However, in the presence of BIIE 0246, a highly selective non-peptide NPY Y2-receptor antagonist, NPY was unable to increase 4-AP I(to) density.	BIIE 0246	28-37	neuropeptide Y	Rattus norvegicus	70-73	
11934810-8	2002	However, in the presence of BIIE 0246, a highly selective non-peptide NPY Y2-receptor antagonist, NPY was unable to increase 4-AP I(to) density.	BIIE 0246	28-37	neuropeptide Y	Rattus norvegicus	98-101	
10725255-9	2000	In the rat colon (a Y(2)/Y(4) bioassay), BIIE0246 (1 microM) completely blocked the contraction induced by PYY(3 - 36), but not that of [Leu(31), Pro(34)]NPY (a Y(1), Y(4) and Y(5) agonist) and hPP (a Y(4) and Y(5) agonist).	BIIE 0246	41-49	neuropeptide Y	Rattus norvegicus	154-157