PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17161886-5 2007 The most potent and selective is SB-334867-A, which has an affinity of 40 nM at OX1R which is at least 50-fold selective over OX2R. 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea 33-44 hypocretin receptor 2 Rattus norvegicus 126-130 12702746-6 2003 The response to orexin A was significantly reduced in the presence of the orexin receptor 1 (OX1R) antagonist SB334867A at concentrations of 1-10 micro M. Single cell reverse transcriptase-polymerase chain reaction revealed expression of mRNA for both OX1R and OX2R in the majority of orexin-sensitive SPNs. 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea 110-119 hypocretin receptor 2 Rattus norvegicus 261-265