PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22693641-8 2012 Interestingly, daily treatment with AT1 receptor blocker irbesartan (50 mg/kg) significantly prevented Ang II-mediated aortic profilin-1 expression, inflammation, and peroxynitrite production in WT mice with enhanced ACE2 levels and the suppression of the Akt-ERK-eNOS signaling pathways. Irbesartan 57-67 thymoma viral proto-oncogene 1 Mus musculus 256-259 27919004-0 2017 Irbesartan ameliorates hyperlipidemia and liver steatosis in type 2 diabetic db/db mice via stimulating PPAR-gamma, AMPK/Akt/mTOR signaling and autophagy. Irbesartan 0-10 thymoma viral proto-oncogene 1 Mus musculus 121-124