PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15188945-8	2004	CONCLUSIONS: Our finding suggests a gender-specific relationship between the G5665T preproendothelin-1 polymorphism and change in SBP in response to antihypertensive treatment with irbesartan or atenolol, suggesting the endothelin pathway to be a common mechanism included in the hypertensive action of the drugs.	Irbesartan	181-191	endothelin 1	Homo sapiens	84-102	
14730203-6	2004	RESULTS: The ET-1 gene was induced with Ang II, which was inhibited with Ang II type 1 receptor antagonist (irbesartan).	Irbesartan	108-118	endothelin 1	Homo sapiens	13-17	
14730203-7	2004	Ang II-enhanced intracellular ROS levels were inhibited by irbesartan and several antioxidants, and antioxidants also suppressed Ang II-induced ET-1 gene expression.	Irbesartan	59-69	endothelin 1	Homo sapiens	144-148