PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20942814-0 2011 Scutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFbeta1 expression and activation of p38-MAPK and ERK1/2. scutellarin 0-11 mitogen activated protein kinase 14 Rattus norvegicus 137-140 31792810-4 2020 Furthermore, expression of p-p38 along with that of tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta(IL-1beta), and inducible nitric oxide synthase (iNOS) in LPS-activated microglia subjected to pretreatment with p38 inhibitor SB203580, p38 activator sc-201214, scutellarin, or a combination of them was evaluated. scutellarin 273-284 mitogen activated protein kinase 14 Rattus norvegicus 29-32 31792810-5 2020 FINDINGS: Scutellarin markedly attenuated the expression of p-p38, p-JNK in AM/BM in MCAO rats and in vitro. scutellarin 10-21 mitogen activated protein kinase 14 Rattus norvegicus 62-65 31792810-11 2020 CONCLUSIONS: The results suggest that scutellarin down-regulates the expression of proinflammatory mediators in AM/BM through suppressing the p-JNK and p-p38 MAPKs. scutellarin 38-49 mitogen activated protein kinase 14 Rattus norvegicus 154-157 31792810-13 2020 Besides, p38 MAPKs activator reverses the effect of scutellarin. scutellarin 52-63 mitogen activated protein kinase 14 Rattus norvegicus 9-12 18442013-6 2007 These results demonstrate that scutellarin can protect PC12 cells from cobalt chloride induced apoptosis by scavenging ROS, inhibiting p38 phosphorylation, up-regulating Bcl-XL expression and decreasing caspase-3 activity, and may reduce the cellular damage in pathological conditions associated with hypoxia-mediated neuronal injury. scutellarin 31-42 mitogen activated protein kinase 14 Rattus norvegicus 135-138