PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34354342-4 2021 Herein, we provide a thorough overview of the current research status of imidazole-based compounds with a wide variety of biological activities including anti-cancer, anti-microbial, anti-inflammatory and their potential mechanisms including topoisomerase IIR catalytic inhibition, focal adhesion kinase (FAK) inhibition, c-MYC G-quadruplex DNA stabilization, and aurora kinase inhibition. imidazole 73-82 protein tyrosine kinase 2 Homo sapiens 282-303 34354342-4 2021 Herein, we provide a thorough overview of the current research status of imidazole-based compounds with a wide variety of biological activities including anti-cancer, anti-microbial, anti-inflammatory and their potential mechanisms including topoisomerase IIR catalytic inhibition, focal adhesion kinase (FAK) inhibition, c-MYC G-quadruplex DNA stabilization, and aurora kinase inhibition. imidazole 73-82 protein tyrosine kinase 2 Homo sapiens 305-308