PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10665514-11	2000	The mean concentration of brinzolamide found in the retina of pigmented rabbits (0.338 microg equivalents/g) after a single dose of 14C-brinzolamide is sufficient to inhibit CA-II.	brinzolamide	26-38	carbonic anhydrase 2	Oryctolagus cuniculus	174-179	
14684332-3	2004	Isozymes CA I and CA II were strongly inhibited by some of these compounds, which showed inhibition constants in the range of 510-1200 nM against CA I and 10-25 nM against CA II, similarly to clinically used sulfonamides, such as acetazolamide, methazolamide, dichlorophenamide, dorzolamide and brinzolamide.	brinzolamide	295-307	carbonic anhydrase 2	Oryctolagus cuniculus	18-23	
14684332-3	2004	Isozymes CA I and CA II were strongly inhibited by some of these compounds, which showed inhibition constants in the range of 510-1200 nM against CA I and 10-25 nM against CA II, similarly to clinically used sulfonamides, such as acetazolamide, methazolamide, dichlorophenamide, dorzolamide and brinzolamide.	brinzolamide	295-307	carbonic anhydrase 2	Oryctolagus cuniculus	172-177