PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25485645-0 2015 The effects of varenicline on sensory gating and exploratory behavior with pretreatment with nicotinic or 5-HT3A receptor antagonists. Varenicline 15-26 5-hydroxytryptamine receptor 3A Homo sapiens 106-112 25485645-3 2015 Varenicline, a nonselective neuronal nicotinic receptor (NNR) agonist and full agonist of 5-HT3A receptors, helps reduce smoking among schizophrenic patients. Varenicline 0-11 5-hydroxytryptamine receptor 3A Homo sapiens 90-96 25485645-8 2015 Collectively, these results indicate that varenicline at low-to-moderate doses may be beneficial against impaired sensory gating in schizophrenia; however, higher doses may induce anxiogenic effects, which can be prevented with antagonists of NNRs or 5-HT3A receptors. Varenicline 42-53 5-hydroxytryptamine receptor 3A Homo sapiens 251-257