PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2775233-3	1989	Procaine and tetracaine inhibited acetylcholinesterase activity competitively at concentrations at which they did not perturb the physical state of the membrane lipid environment, as assessed by steady-state fluorescence polarization, whereas lidocaine and imipramine displayed mixed inhibition kinetics at concentrations at which they induced an enhancement of membrane fluidity.	Procaine	0-8	acetylcholinesterase (Cartwright blood group)	Homo sapiens	34-54	
19007306-5	2009	Additional experiments using AChE inhibitors (amphiphilic procaine hydrochloride, hydrophobic tetrabutylammonium bromide) in the absence or presence of detergent further illustrate the detergent-enzyme-solvent interactions.	Procaine	58-80	acetylcholinesterase (Cartwright blood group)	Homo sapiens	29-33	
8784921-1	1996	A method for preparing various forms of acetylcholinesterase (AChE) from human erythrocyte has been established and they have been characterized in terms of kinetic parameters such as K(m), rate constant (k), turnover number (kcat), specificity constant (ksp), Vmax, half-life (t1/2), IC50 and Ki for tetrabutylammonium hydroxide, procaine and physostigmine in the present study.	Procaine	331-339	acetylcholinesterase (Cartwright blood group)	Homo sapiens	40-60	
8784921-1	1996	A method for preparing various forms of acetylcholinesterase (AChE) from human erythrocyte has been established and they have been characterized in terms of kinetic parameters such as K(m), rate constant (k), turnover number (kcat), specificity constant (ksp), Vmax, half-life (t1/2), IC50 and Ki for tetrabutylammonium hydroxide, procaine and physostigmine in the present study.	Procaine	331-339	acetylcholinesterase (Cartwright blood group)	Homo sapiens	62-66	
20487982-5	1983	The possibility that the results at low ionic strength can be explained on the basis of procaine binding to the active site of acetylcholinesterase (at low concentrations) and also to a peripheral allosteric site (at higher concentrations) is discussed.	Procaine	88-96	acetylcholinesterase (Cartwright blood group)	Homo sapiens	127-147