PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23600203-0	2013	[Comparison of the effect between procaine and 5-aza-dc on wnt inhibitory factor 1 promoter methylation of HepG2].	Procaine	34-42	WNT inhibitory factor 1	Homo sapiens	59-82	
23600203-1	2013	OBJECTIVE: To observe the CpG island methylation status, mRNA and protein expression of the Wnt inhibitory factor-1 (Wif-1) gene with procaine or 5"-Aza-2"-deoxycycytidine (5-aza-dc) on HepG2.	Procaine	134-142	WNT inhibitory factor 1	Homo sapiens	92-115	
23600203-1	2013	OBJECTIVE: To observe the CpG island methylation status, mRNA and protein expression of the Wnt inhibitory factor-1 (Wif-1) gene with procaine or 5"-Aza-2"-deoxycycytidine (5-aza-dc) on HepG2.	Procaine	134-142	WNT inhibitory factor 1	Homo sapiens	117-122	
23600203-7	2013	RESULTS: (1) RT-PCR and Western blot exhibited that both Wif-1 mRNA and Wif-1 protein expression were positive in groups treated with procaine and 5-aza-dc and highly positive in the L0 cells group, but weakly even negative in the HepG2 cells without any treatment, the difference were statistically significant (P < 0.05) (procaine experimental group was higher than that of 5-aza-dc experimental group, P < 0.05).	Procaine	134-142	WNT inhibitory factor 1	Homo sapiens	57-62	
23600203-7	2013	RESULTS: (1) RT-PCR and Western blot exhibited that both Wif-1 mRNA and Wif-1 protein expression were positive in groups treated with procaine and 5-aza-dc and highly positive in the L0 cells group, but weakly even negative in the HepG2 cells without any treatment, the difference were statistically significant (P < 0.05) (procaine experimental group was higher than that of 5-aza-dc experimental group, P < 0.05).	Procaine	134-142	WNT inhibitory factor 1	Homo sapiens	72-77	
23600203-7	2013	RESULTS: (1) RT-PCR and Western blot exhibited that both Wif-1 mRNA and Wif-1 protein expression were positive in groups treated with procaine and 5-aza-dc and highly positive in the L0 cells group, but weakly even negative in the HepG2 cells without any treatment, the difference were statistically significant (P < 0.05) (procaine experimental group was higher than that of 5-aza-dc experimental group, P < 0.05).	Procaine	327-335	WNT inhibitory factor 1	Homo sapiens	57-62	
23600203-7	2013	RESULTS: (1) RT-PCR and Western blot exhibited that both Wif-1 mRNA and Wif-1 protein expression were positive in groups treated with procaine and 5-aza-dc and highly positive in the L0 cells group, but weakly even negative in the HepG2 cells without any treatment, the difference were statistically significant (P < 0.05) (procaine experimental group was higher than that of 5-aza-dc experimental group, P < 0.05).	Procaine	327-335	WNT inhibitory factor 1	Homo sapiens	72-77	
23600203-10	2013	CONCLUSION: Both of procaine and 5-aza-dc can reverse the abnormal methylation of Wif-1 gene.	Procaine	20-28	WNT inhibitory factor 1	Homo sapiens	82-87	
19885602-7	2009	Our results provide the first evidence that procaine and procainamide reactivate WIF-1 in these cancer cells and downregulate the Wnt canonical pathway.	Procaine	44-52	WNT inhibitory factor 1	Homo sapiens	81-86