PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23015612-0 2012 Activated glucose-6-phosphate dehydrogenase is associated with insulin resistance by upregulating pentose and pentosidine in diet-induced obesity of rats. Pentoses 98-105 glucose-6-phosphate dehydrogenase Rattus norvegicus 10-43 23015612-1 2012 Recent studies have shown that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme for the pentose phosphate pathway, was involved in insulin resistance via reduced nicotinamide adenine dinucleotide phosphate, while the roles of pentose were not examined. Pentoses 106-113 glucose-6-phosphate dehydrogenase Rattus norvegicus 31-64 23015612-1 2012 Recent studies have shown that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme for the pentose phosphate pathway, was involved in insulin resistance via reduced nicotinamide adenine dinucleotide phosphate, while the roles of pentose were not examined. Pentoses 106-113 glucose-6-phosphate dehydrogenase Rattus norvegicus 66-70 23015612-6 2012 G6PD activities were increased in the pancreas and liver with upregulated pentose levels in serum, pancreas, and liver of OP rats. Pentoses 74-81 glucose-6-phosphate dehydrogenase Rattus norvegicus 0-4 23015612-9 2012 Our results suggest that the upregulation of G6PD causes an increase in the accumulation of pentose and pentosidine, which might be associated with insulin resistance in the condition of obesity. Pentoses 92-99 glucose-6-phosphate dehydrogenase Rattus norvegicus 45-49 1460245-7 1992 The inhibition of NADP-isocitrate dehydrogenase coupled with glucose 6-phosphate dehydrogenase indicates reduced generation of NADPH2 and pentoses for the synthesis of fatty acids and nucleotides. Pentoses 138-146 glucose-6-phosphate dehydrogenase Rattus norvegicus 61-94 19526128-2 2009 A negative correlation was revealed between locomotion of Wistar rats in the open field and activity of glucose-6-phosphate dehydrogenase in the sensorimotor cortex, especially in efferent layer V neurons and neurons of the caudate nucleus and nucleus accumbens, which attested to different capacity of the brain in Wistar rats with high and low open-field locomotion to regeneration of phosphopyridine nucleotides (NADP(+)) and production of pentoses via the pentose phosphate shunt. Pentoses 443-451 glucose-6-phosphate dehydrogenase Rattus norvegicus 104-137 12717738-2 2003 G6PDH is the key rate-limiting enzyme in the pentose pathway and the expression of its gene has been shown to be redox-sensitive. Pentoses 45-52 glucose-6-phosphate dehydrogenase Rattus norvegicus 0-5 8901462-1 1996 The capacity of the oxidative pentose pathway (PPP) in the heart is limited, since the activity of glucose-6-phosphate dehydrogenase (G-6-PD), the first and regulating enzyme of this pathway, is very low. Pentoses 30-37 glucose-6-phosphate dehydrogenase Rattus norvegicus 99-132 8901462-1 1996 The capacity of the oxidative pentose pathway (PPP) in the heart is limited, since the activity of glucose-6-phosphate dehydrogenase (G-6-PD), the first and regulating enzyme of this pathway, is very low. Pentoses 30-37 glucose-6-phosphate dehydrogenase Rattus norvegicus 134-140 2753047-2 1989 The activities of the NADP+-dependent dehydrogenases of the pentose-phosphate pathway (glucose-6-phosphate dehydrogenase and phosphogluconate dehydrogenase) were detected in the purified peroxisomal fraction as well as in the cytosol. Pentoses 60-67 glucose-6-phosphate dehydrogenase Rattus norvegicus 87-120 3790254-4 1986 Even under conditions of increased NADPH requirements (infusion of tert-butylhydroperoxide) and a diminished 14CO2 production from glucose via the citrate cycle (in the presence of oleate as additional substrate) or enhanced activity of glucose-6-phosphate dehydrogenase (pretreatment with isoproterenol), a substrate flux through the pentose cycle was not detectable. Pentoses 335-342 glucose-6-phosphate dehydrogenase Rattus norvegicus 237-270 3976016-1 1985 Repeated supercoolings down to rectal temperatures (19-20 degrees C) results in the different changes in the dehydrogenase activity of pentose and glucuronate pathways in the rat brain: the activity of the pentose cycle oxidative enzymes (glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase) lowers considerably and that of VDP-glucose dehydrogenase rises. Pentoses 135-142 glucose-6-phosphate dehydrogenase Rattus norvegicus 239-272 3976016-1 1985 Repeated supercoolings down to rectal temperatures (19-20 degrees C) results in the different changes in the dehydrogenase activity of pentose and glucuronate pathways in the rat brain: the activity of the pentose cycle oxidative enzymes (glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase) lowers considerably and that of VDP-glucose dehydrogenase rises. Pentoses 206-213 glucose-6-phosphate dehydrogenase Rattus norvegicus 239-272 31550253-13 2019 In contrast, the pentose phosphate pathway seemed to be increased as the hepatic gene expression of glucose-6-phosphate dehydrogenase (G6PD) was higher in 1-triple TTA treated rats compared to controls. Pentoses 17-34 glucose-6-phosphate dehydrogenase Rattus norvegicus 100-133 1036242-2 1976 Three enzymes selected as representative of major metabolic pathways (malic dehydrogenase, of the citric acid cycle, lactic dehydrogenase, of glycolysis and glucose-6-phosphate dehydrogenase, of the pentose pathway) were measured by quantitative histochemical methods in individual hypothalamic nuclei during the 5-day estrous cycle of adult rats. Pentoses 199-206 glucose-6-phosphate dehydrogenase Rattus norvegicus 157-190 31550253-13 2019 In contrast, the pentose phosphate pathway seemed to be increased as the hepatic gene expression of glucose-6-phosphate dehydrogenase (G6PD) was higher in 1-triple TTA treated rats compared to controls. Pentoses 17-34 glucose-6-phosphate dehydrogenase Rattus norvegicus 135-139 30379558-2 2018 DHEA possesses an inhibitory action on glucose-6-phosphate dehydrogenase (G6PD), the first pentose-phosphate pathway enzyme that reduces NADP+ to NADPH. Pentoses 91-98 glucose-6-phosphate dehydrogenase Rattus norvegicus 39-72 30379558-2 2018 DHEA possesses an inhibitory action on glucose-6-phosphate dehydrogenase (G6PD), the first pentose-phosphate pathway enzyme that reduces NADP+ to NADPH. Pentoses 91-98 glucose-6-phosphate dehydrogenase Rattus norvegicus 74-78 27207834-6 2016 The pentose pathway was activated as indicated by increased G6PD activity and NADPH level. Pentoses 4-11 glucose-6-phosphate dehydrogenase Rattus norvegicus 60-64