PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34459128-8 2021 Moreover, single-cell regulatory network inference and clustering (SCENIC) analysis reveals the gene regulatory networks and suggests the JUN signaling pathway as a potential therapeutic target for treatment of ovarian cancer, which is validated using the JUN/AP-1 inhibitor T-5224. 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxy-1,2-benzisoxazol-6-yl)methoxy)phenyl)propionic acid 275-281 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 260-264 31929749-6 2020 Knockdown of two AP-1 subunits (c-Jun and c-FOS) or blockage of AP-1 signaling with two inhibitors T-5224 and SR11302 could cause the downregulation of TGFB1, whereas knockdown of two NF-kappaB subunits (p65 and p50) or blockage of NF-kappaB signaling with two inhibitors TPCA1 and BOT-64 could not change the expression of TGFB1. 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxy-1,2-benzisoxazol-6-yl)methoxy)phenyl)propionic acid 99-105 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 64-68