PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12203101-6	2002	Western blot analysis revealed that Cl-F-araA induced a dose- and time-dependent downregulation of Bcl-X(L) and Mcl-1 proteins, and a dose- and time-dependent dephosphorylation of Akt and its downstream effectors (Bad, FKHRL1), particularly in vivo.	Clofarabine	36-45	AKT serine/threonine kinase 1	Homo sapiens	180-183	
24413065-6	2014	In all three cell lines [Gem+Clo+Ed] decreased the level of phosphorylation of the pro-survival protein AKT and activated the stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) stress signaling pathway, which in J45.01 cells resulted in the phosphorylation and heterodimerization of the transcription factors ATF2 and c-Jun.	Clofarabine	29-32	AKT serine/threonine kinase 1	Homo sapiens	104-107	
23146690-7	2013	Taken together, the data provide evidence that the synergistic antiproliferative effect of resveratrol and clofarabine is linked to the inhibition of Akt and Sp1 activities, and suggest that this combination may have therapeutic value in treatment of malignant mesothelioma.	Clofarabine	107-118	AKT serine/threonine kinase 1	Homo sapiens	150-153