PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28442502-7	2017	Clofarabine, a purine nucleoside analogue that inhibits RRM1, induced growth arrest and apoptosis in p53 wild-type cell lines.	Clofarabine	0-11	tumor protein p53	Homo sapiens	101-104	
26819918-2	2015	Clofarabine-induced defect in DNA replication, induces p53 and subsequently P53R2 genes as subunit of RR.	Clofarabine	0-11	tumor protein p53	Homo sapiens	55-58	
24239893-4	2014	Resveratrol, in combination with clofarabine, time-dependently induced a strong cytotoxic effect with the nuclear accumulation of phospho-p53 (p-p53) in MSTO-211H cells, but not in normal mesothelial MeT-5A cells.	Clofarabine	33-44	tumor protein p53	Homo sapiens	138-141	
24239893-4	2014	Resveratrol, in combination with clofarabine, time-dependently induced a strong cytotoxic effect with the nuclear accumulation of phospho-p53 (p-p53) in MSTO-211H cells, but not in normal mesothelial MeT-5A cells.	Clofarabine	33-44	tumor protein p53	Homo sapiens	145-148	
24239893-10	2014	Taken together, these results demonstrate that resveratrol and clofarabine synergistically elicit apoptotic signal via a p53-dependent pathway, and provide a scientific rationale for clinical evaluation of resveratrol as a promising chemopotentiator in MM.	Clofarabine	63-74	tumor protein p53	Homo sapiens	121-124	
24144307-5	2014	[Flu + Clo + Bu + SAHA] resulted in synergistic cytotoxicity, which can be attributed to (1) activated DNA-damage response and cell cycle checkpoint activation through the ATM-CHK2-P53 (or P73) pathway or ATM-CHK2-cdc25-cdc2 pathway, (2) histone modifications and (3) activated apoptosis pathway.	Clofarabine	7-10	tumor protein p53	Homo sapiens	181-184	
23648290-7	2013	Exposure of MM cells to [Gem+Clo] also decreased the level of ribosomal RNA (rRNA), which might have resulted in nucleolar stress, as reported previously, and caused a p53-dependent cell death.	Clofarabine	29-32	tumor protein p53	Homo sapiens	168-171	
23648290-8	2013	A reduction by approximately 50% in the cytotoxicity of Gem and Clo was observed in the presence of pifithrin alpha, a p53 inhibitor.	Clofarabine	64-67	tumor protein p53	Homo sapiens	119-122