PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23729661-9 2013 Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3 transfected human embryonic kidney 293 (HEK293) cells transported axitinib to a minor extent but uptake into suspended hepatocytes was not inhibited by rifamycin SV suggesting that high passive permeability predominates. Axitinib 131-139 solute carrier organic anion transporter family member 1B1 Homo sapiens 0-42 23729661-9 2013 Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3 transfected human embryonic kidney 293 (HEK293) cells transported axitinib to a minor extent but uptake into suspended hepatocytes was not inhibited by rifamycin SV suggesting that high passive permeability predominates. Axitinib 131-139 solute carrier organic anion transporter family member 1B1 Homo sapiens 44-51 22170007-1 2012 PURPOSE: Axitinib, an orally administered inhibitor of vascular endothelial growth factor 1, 2 and 3, is primarily metabolized by cytochrome P450 (CYP) 3A4/5 but is also a substrate for CYP1A2, CYP2C19, UDP-glucuronosyltransferase (UGT)1A1 and the drug transporters P-glycoprotein (encoded by the ABCB1 gene) and OATP1B1 (encoded by SLC01B1). Axitinib 9-17 solute carrier organic anion transporter family member 1B1 Homo sapiens 313-320