PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19382214-6 2009 We also report that long-term inhibition of cholesterol biosynthesis with 25-hydroxycholesterol blocks IGF-I stimulated Akt phosphorylation and cell survival. 25-hydroxycholesterol 74-95 insulin like growth factor 1 Homo sapiens 103-108 3311719-11 1987 Insulin treatment did not affect P450 SCC activity, whereas IGF-I treatment significantly stimulated P450 SCC activity by 19-36%, as measured by the conversion of 25-hydroxycholesterol to progesterone. 25-hydroxycholesterol 163-184 insulin like growth factor 1 Homo sapiens 60-65