PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21698267-6	2011	ORP8, previously shown to bind 25-hydroxycholesterol, was now shown to bind also cholesterol in vitro.	25-hydroxycholesterol	31-52	oxysterol binding protein like 8	Homo sapiens	0-4	
27530118-0	2016	Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol.	25-hydroxycholesterol	73-94	oxysterol binding protein like 8	Homo sapiens	0-43	
27530118-4	2016	Here, we report that 25-hydroxycholesterol (OHC) induced apoptosis of the hepatoma cell lines, HepG2 and Huh7, via the endoplasmic reticulum (ER) stress response pathway, and ORP8 overexpression resulted in a similar cell response as 25-OHC, indicating a putative functional relationship between oxysterol cytotoxicity and ORP8.	25-hydroxycholesterol	21-42	oxysterol binding protein like 8	Homo sapiens	175-179	
27530118-4	2016	Here, we report that 25-hydroxycholesterol (OHC) induced apoptosis of the hepatoma cell lines, HepG2 and Huh7, via the endoplasmic reticulum (ER) stress response pathway, and ORP8 overexpression resulted in a similar cell response as 25-OHC, indicating a putative functional relationship between oxysterol cytotoxicity and ORP8.	25-hydroxycholesterol	21-42	oxysterol binding protein like 8	Homo sapiens	323-327	
27530118-8	2016	Taken together, the present study suggests that ORP8 may mediate the cytotoxicity of 25-OHC.	25-hydroxycholesterol	85-91	oxysterol binding protein like 8	Homo sapiens	48-52	
17991739-3	2008	ORP8 is localized in the endoplasmic reticulum (ER) via its C-terminal transmembrane span and binds 25-hydroxycholesterol, identifying it as a new ER oxysterol-binding protein.	25-hydroxycholesterol	100-121	oxysterol binding protein like 8	Homo sapiens	0-4