PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34256859-0 2021 Exosomal miR-100-5p inhibits osteogenesis of hBMSCs and angiogenesis of HUVECs by suppressing the BMPR2/Smad1/5/9 signalling pathway. mir-100-5p 9-19 bone morphogenetic protein receptor type 2 Homo sapiens 98-103 34256859-10 2021 The target relationship between miR-100-5p and BMPR2 was predicted and confirmed by a dual luciferase reporter assay and WB. mir-100-5p 32-42 bone morphogenetic protein receptor type 2 Homo sapiens 47-52 34256859-13 2021 MiR-100-5p expression was upregulated in the NONFH exosomes and inhibited the osteogenesis of hBMSCs and angiogenesis of HUVECs by targeting BMPR2 and suppressing the BMPR2/SMAD1/5/9 signalling pathway. mir-100-5p 0-10 bone morphogenetic protein receptor type 2 Homo sapiens 141-146 34256859-13 2021 MiR-100-5p expression was upregulated in the NONFH exosomes and inhibited the osteogenesis of hBMSCs and angiogenesis of HUVECs by targeting BMPR2 and suppressing the BMPR2/SMAD1/5/9 signalling pathway. mir-100-5p 0-10 bone morphogenetic protein receptor type 2 Homo sapiens 167-172 34256859-14 2021 Silencing miR-100-5p expression rescued the reduction in osteogenesis and angiogenesis caused by the NONFH exosomes by activating the BMPR2/SMAD1/5/9 signalling pathway. mir-100-5p 10-20 bone morphogenetic protein receptor type 2 Homo sapiens 134-139 34256859-15 2021 CONCLUSION: The NONFH exosomal miR-100-5p can lead to NONFH-like damage by targeting BMPR2 and suppressing the BMPR2/SMAD1/5/9 signalling pathway, which may be involved in the pathophysiological mechanisms of nontraumatic osteonecrosis of the femoral head (NONFH). mir-100-5p 31-41 bone morphogenetic protein receptor type 2 Homo sapiens 85-90 34256859-15 2021 CONCLUSION: The NONFH exosomal miR-100-5p can lead to NONFH-like damage by targeting BMPR2 and suppressing the BMPR2/SMAD1/5/9 signalling pathway, which may be involved in the pathophysiological mechanisms of nontraumatic osteonecrosis of the femoral head (NONFH). mir-100-5p 31-41 bone morphogenetic protein receptor type 2 Homo sapiens 111-116 35356885-10 2022 The upregulation of miR-100-5p in rBMSCs reduced the expressions of ALP, RUNX2, Col1, and BMPR2, and inhibited the osteogenic differentiation and migration abilities of rBMSCs. mir-100-5p 20-30 bone morphogenetic protein receptor type 2 Homo sapiens 90-95