PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19447225-0 2009 HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages. Lopinavir 23-32 tumor necrosis factor Mus musculus 41-50 19447225-6 2009 Lopinavir-induced cytosolic translocation of HuR and TNF-alpha and IL-6 synthesis was attenuated by specific chemical inhibitor of MEK (PD98058) or over-expression of dominant negative mutant of MEK1. Lopinavir 0-9 tumor necrosis factor Mus musculus 53-62 19447225-7 2009 In addition, we demonstrated that lopinavir-induced ERK activation and TNF-alpha and IL-6 expression were completely inhibited in macrophages from CHOP null mice. Lopinavir 34-43 tumor necrosis factor Mus musculus 71-80 18599597-3 2008 Superfusion with the GJ blockers 18-alpha-glycyrrhetinic acid (AGA; 75 microM) or 18-beta-glycyrrhetinic acid (50 microM) abolished the TNF-alpha-induced increase in LAV and LPV; carbenoxolone (75 microM) or oleamide (100 microM) reduced LAV by 50 and 75%, respectively, and LPV to a lesser extent. Lopinavir 174-177 tumor necrosis factor Mus musculus 136-145 18599597-3 2008 Superfusion with the GJ blockers 18-alpha-glycyrrhetinic acid (AGA; 75 microM) or 18-beta-glycyrrhetinic acid (50 microM) abolished the TNF-alpha-induced increase in LAV and LPV; carbenoxolone (75 microM) or oleamide (100 microM) reduced LAV by 50 and 75%, respectively, and LPV to a lesser extent. Lopinavir 275-278 tumor necrosis factor Mus musculus 136-145