PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25261710-1 2014 Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. Lopinavir 19-28 PGP Canis lupus familiaris 53-67 25261710-1 2014 Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. Lopinavir 19-28 PGP Canis lupus familiaris 69-73 25261710-1 2014 Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. Lopinavir 30-33 PGP Canis lupus familiaris 53-67 25261710-1 2014 Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. Lopinavir 30-33 PGP Canis lupus familiaris 69-73 25261710-3 2014 In the present study, dipeptide prodrug approach was employed to circumvent efflux pumps (P-gp and MRP2) and CYP3A4 mediated metabolism of LPV. Lopinavir 139-142 PGP Canis lupus familiaris 90-94 17664327-8 2007 Pgp inhibition constants ranged from 10.3 microM (lopinavir) to >100 microM (amprenavir, indinavir, and darunavir). Lopinavir 50-59 PGP Canis lupus familiaris 0-3 17451894-0 2007 Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor. Lopinavir 40-49 PGP Canis lupus familiaris 5-9