PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27633141-0	2016	The natural anthraquinones from Rheum palmatum induced the metabolic disorder of melatonin by inhibiting human CYP and SULT enzymes.	Anthraquinones	12-26	peptidylprolyl isomerase G	Homo sapiens	111-114	
33438235-5	2021	Here, in silico (quantitative structure-activity relationship modeling) and in vitro (human recombinant enzymes and liver microsomes) methods were used to identify inhibitors of five major CYP isoforms (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) among 22 anthraquinones.	Anthraquinones	257-271	peptidylprolyl isomerase G	Homo sapiens	189-192	
33438235-8	2021	Finally, plasma concentrations of the five anthraquinones in animal and humans were identified in the literature and compared to their in vitro inhibition potency (IC50 values) towards CYP activities.	Anthraquinones	43-57	peptidylprolyl isomerase G	Homo sapiens	185-188