PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20353011-5	2009	RESULT: Western blot and semiquantive RT-PCR showed that serum containing total anthraquinone in rheum prepared from rats treated with 4.5 g x kg(-1) x d(-1) of total anthraquinone in rheum could inhibit the expression of mRNA and protein levels of AQP 4 in LoVo cells (P<0.01).	Anthraquinones	80-93	aquaporin 4	Rattus norvegicus	249-254	
20353011-5	2009	RESULT: Western blot and semiquantive RT-PCR showed that serum containing total anthraquinone in rheum prepared from rats treated with 4.5 g x kg(-1) x d(-1) of total anthraquinone in rheum could inhibit the expression of mRNA and protein levels of AQP 4 in LoVo cells (P<0.01).	Anthraquinones	167-180	aquaporin 4	Rattus norvegicus	249-254	
19065897-0	2008	[Regulatory effect of anthraquinone derivatives from rhubarb on aquaporin 4 expression in colon of rats and in LoVo cell line].	Anthraquinones	22-35	aquaporin 4	Rattus norvegicus	64-75	
19065897-1	2008	OBJECTIVE: To investigate the cathartic effect of total anthraquinone (AQ) from rhubarb on SD rats and its regulatory effect on aquaporin 4 (AQP4) expression in rat colon and in vitro cultured LoVo cell line.	Anthraquinones	56-69	aquaporin 4	Rattus norvegicus	128-139	
19065897-1	2008	OBJECTIVE: To investigate the cathartic effect of total anthraquinone (AQ) from rhubarb on SD rats and its regulatory effect on aquaporin 4 (AQP4) expression in rat colon and in vitro cultured LoVo cell line.	Anthraquinones	56-69	aquaporin 4	Rattus norvegicus	141-145	
19065897-1	2008	OBJECTIVE: To investigate the cathartic effect of total anthraquinone (AQ) from rhubarb on SD rats and its regulatory effect on aquaporin 4 (AQP4) expression in rat colon and in vitro cultured LoVo cell line.	Anthraquinones	71-73	aquaporin 4	Rattus norvegicus	128-139	
19065897-1	2008	OBJECTIVE: To investigate the cathartic effect of total anthraquinone (AQ) from rhubarb on SD rats and its regulatory effect on aquaporin 4 (AQP4) expression in rat colon and in vitro cultured LoVo cell line.	Anthraquinones	71-73	aquaporin 4	Rattus norvegicus	141-145	
19065897-8	2008	CONCLUSION: At the same time of playing cathartic action, total AQ of rhubarb can effectively down-regulate the expression of AQP4 in rat"s proximal colon; rhein/emodin can suppress the AQP4 expression in LoVo cells in vitro.	Anthraquinones	64-66	aquaporin 4	Rattus norvegicus	126-130