PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24043260-4 2014 Using a murine model of laser-induced CNV, we determined that reduced Rap1 activity in RPE/choroid occurred with CNV formation and that activation of Rap1 by 2"-O-Me-cAMP (8CPT)-reduced laser-induced CNV via inhibiting NADPH oxidase-generated ROS. 2"-o-me 158-165 RAS-related protein 1a Mus musculus 150-154